Title: Week 10- UNIT 4_3: Transcription
Course: Biochemistry

Introduction

Transcription is the process of making an RNA copy of a gene sequence. This copy, called a messenger RNA (mRNA) molecule, leaves the cell nucleus and enters the cytoplasm, where it directs the synthesis of the protein, which it encodes.Transcription is different in prokaryotes and eukaryotes and is composed of three steps : initiation , elongation and termination.

Expectation

This unit focuses on how transcription happens. Transcription is the first part of the protein synthesis, while the second d part : translation will be discussed in the next chapter.

Course outline

1. Central Dogma
2. Prokaryotic transcription
3. Eukaryotic transcription
4. mRNA processing in Eukaryotes

Learning outcomes

At the end of this unit, you should be able to:

- Describe the transcription process in bacteria.
- List and explain the different steps in Eukaryotic transcription
- Compare and contrasts the three types of RNA polymerases in Eukaryotes
- Distinguish between Prokaryotic and Eukaryotic transcription
- Describe the different steps in mRNA processing